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Other Cancer Risks

Based on information provided by the Cancer Institute, NSW. These other cancers can be associated with BRCA1 and BRCA2.

  • BRCA1- breast cancer, ovarian and fallopian tube cancer, primary peritoneal cancer
  • BRCA2 - breast cancer, ovarian and fallopian tube cancer, primary peritoneal cancer, prostate cancer, pancreatic cancer, melanoma. We may also discuss risk of stomach cancer with rare ethnic groups.

Overview:
These other cancers (below) have been linked to hereditary breast or ovarian cancer. Some cancers are associated with BRCA mutations; other cancer syndromes may be associated with other types of cancer not listed here. As more research is done, more will be understood. Your Cancer Geneticist or Genetic Counsellor will know more up-to-date information and recommend the best screening options available.

Fallopian tube cancer:
Primary fallopian tube cancer (PFTC), often just tubal cancer, is a malignant neoplasm that originates from the fallopian tube. It is very similar to ovarian cancer.

Melanoma:
Melanoma is a malignant tumour of melanocytes. Such cells are found predominantly in skin and are responsible for the production of the dark pigment melanin. Melanoma is one of the less common types of skin cancer, but causes the majority (75%) of skin cancer related deaths.Melanocytes are normally present in skin.


Pancreatic cancer:
Pancreatic cancer is a malignant neoplasm of the panceatic gland, responsible for insulin

Primary peritoneal cancer:
Primary peritoneal cancer or carcinoma is a cancer of the cells lining the peritoneum, or abdominal cavity. It is very similar to ovarian cancer.

Prostate cancer:

Prostate cancer is a common form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing and occur in men aged over 50.

Stomach cancer:
Gastric cancer can develop in any part of the lining of the stomach. A common basteria called H. Pylori and smoking are the main causes of stomach cancer.

For more information please read the fact sheets on the Cancer Institute website here


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