What types of risks do men have with a BRCA mutation?
Men with a BRCA gene mutation have a higher risk of developing breast cancer, prostate cancer and skin cancer (melanoma). In some men (and women), BRCA2 gene mutations have been associated with an increased risk of lymphoma, melanoma, and cancers of the pancreas, gallbladder, bile duct, and stomach. Furthermore, these cancers are more likely to develop at a younger age in men with a BRCA mutation. Men with a BRCA mutation have a lower chance overall of developing cancer than do women with a mutation.
Could I have inherited the BRCA gene fault from my father?
Yes. Both women and men can carry the defective gene . They also have a 50/50 chance of passing it on to their child.
I am a man, should I get testing? Should my dad get testing?
Men from families with a history of breast and ovarian cancer should consider testing for a BRCA gene mutation particularly if any of the breast cancers occurred before age 50 (in either female or male relatives). Men with breast cancer themselves are highly likely to have a BRCA mutation and should consider testing. Men who have prostate cancer and a family history of breast cancer should also think about testing.
I am a man with a BRCA mutation, what can I do to reduce my risk?
Men who know they carry a BRCA gene mutation can take proactive steps such as getting screened regularly for some of the cancers associated with the mutation, such as prostate cancer screening, skin examinations for melanoma. Men with a BRCA mutation should also seek medical advice about any changes in their breasts.
It is important to share your BRCA result with your family when it is appropriate as it may be life saving information for your sisters, mother and daughters.
Further information below:
Men With BRCA Gene Mutations Unaware of Cancer Risks
"BRCA2 and prostate cancer"
